Bisphosphonates

NICE CKS Osteoporosis - prevention of fragility fractures, Prescribing information, Bisphosphonates. Last revised Jan 2025. NICE BNF Treatment summary Osteoporosis NICE BNF Alendronic acid, Risedronate sodium, Zoledronic acid

Background Information

Prescription Information

 
Hypocalcaemia and vitamin D deficiency (if any) must be corrected before giving bisphosphonates. As bisphosphonates may worsen hypocalcemia by reducing bone resorption which releases calcium, potentially resulting in arrhythmias or seizures.

References

Author: Adams Lau
Reviewer:
Last Edited: 23/02/25